Wednesday, May 03, 2006

Hepatology: Liver function tests

1. SGOT/SGPT in an alcoholic patient is >2 because:
a) SGOT is excessively released in alcoholic hepatitis
b) SGPT is poorly synthesized due to pyridoxine deficiency
c) Alcohol induced change in enzyme synthesis
d) Observation is an artifact due to interference of alcohol with SGPT estimation

2. GGT/ALP ratio diagnostic of alcohol induced liver injury:
a) 1
b) 1.5
c) 2
d) 2.5
e) 3
f) 3.5

3. GGT is synthesized from all except:
a) Liver
b) Pancreas
c) Kidney
d) Heart
e) Biliary tract
f) Lungs
g) Spleen

4. An alcoholic after binge drinking is referred to you with his PT>16s and S.Bilirubin>5mg/dl, and Albumin>3 gm/dl, your comment as a hepatologist is that:
a) Discrimination index is 60, his prognosis is good.
b) Discrimination index is 70,his prognosis is good
c) Discrimination index is 60,prognosis is bad
d) Discrimination index is 70,prognosis is bad

5. All the following are synthesized in liver except:
a) Prothrombin
b) Alpha 1 antitrypsin
c) Anti hemophilic factor
d) Gamma globulins

6. All the following helps to determine the biliary origin of ALP except:
a) GGT
b) Amino peptidase
c) 5’- Nucleotidase
d) LDH-1
e) Bilirubin

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